Prisma 25ST

Löwenstein Prisma 25ST is an advanced BiPAP ST machine designed for patients with obstructive sleep apnea, COPD, hypoventilation syndrome, neuromuscular disorders, and other respiratory conditions. Srivari Healthcare provides genuine products, expert consultation, installation support, and PAN India delivery.

What Is the Prisma 25ST?

The Prisma 25ST is a BiLevel-ST (bilevel spontaneous/timed) therapy device manufactured by Löwenstein Medical, a German respiratory technology company. Unlike a standard CPAP machine, which delivers one constant pressure, the Prisma 25ST delivers two independently adjustable pressures — a higher pressure on inhalation (IPAP) and a lower pressure on exhalation (EPAP) — and can trigger a breath on its own if a patient's natural breathing pauses for too long. This makes it suitable for a wider range of respiratory conditions than CPAP or Auto CPAP alone, including complex and mixed sleep apnea, COPD with hypoventilation, and certain neuromuscular conditions that affect breathing.

Who Should Use the Prisma 25ST

• Patients with complex or treatment-emergent sleep apnea — where obstructive events persist or central apneas appear despite adequate CPAP pressure.
• Patients with mixed sleep apnea — a combination of obstructive and central events on the same diagnostic study.
• COPD patients with chronic hypoventilation — who need pressure support beyond what CPAP provides to help clear CO₂.
• Patients with neuromuscular disease affecting the respiratory muscles — where a backup breath rate adds a margin of safety.
• Patients discharged from hospital on BiLevel-ST therapy — continuing the same therapy mode at home under physician guidance.

Who Should Avoid It — or Use It Only Under Supervision

• Patients newly diagnosed with straightforward obstructive sleep apnea, who have not first tried standard CPAP or Auto CPAP — a bilevel device is rarely the first-line choice here and is usually prescribed only after a sleep physician determines CPAP is insufficient.
• Anyone without a formal diagnostic sleep study or physician prescription — pressure settings, IPAP/EPAP range, and backup rate must be configured to an individual's clinical needs, not self-selected.
• Patients with untreated pneumothorax, or specific contraindications to positive airway pressure therapy flagged by their treating physician.

This section is general information, not a substitute for a consultation with a pulmonologist or sleep physician. Always confirm suitability with your treating doctor before starting or changing any BiLevel-ST therapy.

How the Prisma 25ST Works

Understanding ST Mode and autoS/T

"ST" stands for Spontaneous/Timed. In Spontaneous (S) mode, the device senses each natural breath and cycles between IPAP and EPAP in time with it. In Timed (T) mode, the device delivers breaths at a fixed backup rate regardless of the patient's own effort. ST mode combines both: it follows the patient's spontaneous breathing whenever it is detected, and automatically delivers a backup breath at the set rate if a pause in breathing is detected — the defining safety feature of a bilevel-ST device over a plain bilevel (S-only) unit.

The Prisma 25ST's autoS/T mode goes a step further: instead of a single fixed backup rate, the device continuously analyses the patient's own breathing pattern and adjusts the backup frequency and pressure support automatically, aiming to stay close to the patient's natural rhythm rather than imposing a rigid rate. Löwenstein's Forced Oscillation Technique (FOT) supports this by helping the device tell the difference between an obstructive event (airway blocked) and a central event (no effort to breathe), so it can respond appropriately to each.

Prisma 25ST vs CPAP vs Auto CPAP

Feature	Standard CPAP	Auto CPAP (APAP)	Prisma 25ST (BiLevel-ST)
Pressure delivery	One fixed pressure	One pressure, auto-adjusted within a range	Two independent pressures (IPAP/EPAP), 4–25 hPa
Backup breath if apnea occurs	No	No	Yes — autoBackup Frequency (PRIO S+)
Typical first-line use	Uncomplicated OSA	Uncomplicated to moderate OSA	Complex/mixed apnea, COPD hypoventilation, NMD
Central apnea detection	No	Limited	Yes — Forced Oscillation Technique (FOT)
Who typically prescribes it	Sleep physician, first-line	Sleep physician, first-line	Sleep physician / pulmonologist, after CPAP is found insufficient

Prisma 25ST vs Prisma SMART vs Prisma SMART plus vs Prisma VENT 40

Model	Category	Best suited for
Prisma SMART (Auto CPAP)	Auto CPAP	Straightforward obstructive sleep apnea, first-time CPAP users
Prisma SMART plus	Auto CPAP	OSA patients wanting additional comfort/data features over the base SMART
Prisma 25ST	BiLevel-ST	Complex/mixed apnea, COPD hypoventilation, neuromuscular disease
Prisma VENT 40 (NIV)	Home mechanical ventilator	Chronic respiratory failure requiring full non-invasive ventilation, often with battery backup for mobility/travel

In short: move from left to right in this table as clinical need increases — Auto CPAP for uncomplicated OSA, Prisma 25ST when bilevel support and a safety backup rate are required, and the Prisma VENT 40 when a patient needs full ventilatory support rather than just pressure-support therapy. Your pulmonologist or sleep physician determines which category fits your diagnosis.

Clinical Applications

Condition	How the Prisma 25ST is used
Obstructive Sleep Apnea (OSA), complex presentation	Bilevel pressure support with backup rate when CPAP alone hasn't controlled events
Central Sleep Apnea (CSA) / mixed apnea	autoS/T mode provides a backup breath during central events
Chronic Obstructive Pulmonary Disease (COPD)	Bilevel support assists ventilation in patients with chronic CO₂ retention
Neuromuscular disease affecting respiratory muscles	Backup frequency provides a safety margin when a patient's own respiratory drive is reduced
Post-hospital respiratory support	Continuation of bilevel-ST therapy started in hospital, under physician supervision at home

Full Technical Specifications

Parameter	Detail
Therapy modes	CPAP, APAP, S, T, S/T, autoS, autoS/T
IPAP range	4–25 hPa (cmH₂O)
EPAP range	4–20 hPa (cmH₂O)
Backup respiratory rate	Automatic, via autoBackup Frequency (PRIO S+)
Apnea differentiation	Forced Oscillation Technique (FOT) — distinguishes central vs obstructive events
Comfort features	softSTART (pressure ramp), autoTriLevel
Sound level	Approx. 26.5 dB(A)
Weight	Approx. 1.4 kg
Display	Full-colour touchscreen with SCOPES indication-specific presets
Data connectivity	SD card, LAN, prisma CLOUD, prisma APP
Build / origin	CE-marked, manufactured in Germany by Löwenstein Medical
Power	Standard mains AC; check DC/travel adapter compatibility with your supplier for air travel

Specification values are as published by Löwenstein Medical for the Prisma 25ST at the time of writing. Always confirm current specifications and any regional variations with Srivari Healthcare before purchase.

Mask & Humidifier Compatibility

The Prisma 25ST works with standard CPAP/BiPAP full-face and nasal masks from major manufacturers, connected via a standard 22mm circuit. Löwenstein's own heated humidifier range is designed to integrate directly with the Prisma series for temperature and humidity control; ask Srivari Healthcare to confirm the exact humidifier model recommended for your unit and prescription.

Accessories Included

• Heated humidifier (Löwenstein-compatible)
• Heated and standard tubing (22mm)
• Full-face and nasal mask options, multiple sizes
• SD card for data logging
• Filters (standard and fine/allergy-grade)
• Carry case for travel

Maintenance & Cleaning Guide

1. Wipe the device exterior with a soft, dry or slightly damp cloth — never submerge the unit itself.
2. Wash the mask cushion and headgear daily with mild soap and water; rinse thoroughly and air-dry away from direct sunlight.
3. Clean the tubing weekly with mild soapy water; rinse and hang to dry fully before reconnecting.
4. Empty, rinse and refill the humidifier chamber daily with distilled or cooled boiled water only.
5. Check and replace the air filter every 1–2 months, or sooner if visibly discoloured or in dusty environments.
6. Book an annual professional service check with Srivari Healthcare to verify pressure calibration and motor condition.

Warranty & Servicing

The Prisma 25ST is covered by Löwenstein Medical's manufacturer warranty; exact terms depend on your invoice date and are confirmed at the time of purchase. Srivari Healthcare, as an authorised dealer, handles warranty registration, in-warranty service coordination, and post-warranty maintenance and repair support locally in Chennai.

Buying vs Renting in Chennai

The Prisma 25ST is available for outright purchase through Srivari Healthcare at ₹75,000 (plus applicable GST). For patients who need bilevel-ST therapy on a short-term or trial basis — for example immediately after hospital discharge, or while a titration study confirms long-term settings — BiPAP rental plans are also available; ask our team for current bilevel-ST rental availability and pricing, as these can vary based on device availability and rental duration.

Why Buy From Srivari Healthcare

Srivari Healthcare is an authorised dealer for Löwenstein Medical in Chennai, providing genuine devices, manufacturer-backed warranty, and in-house clinical support rather than a purely transactional sale.

Why Doctors Trust Us

Product information on this page is medically reviewed by a practicing pulmonologist and sleep specialist (see review credit below), and our team coordinates directly with prescribing physicians on titration and follow-up.

Why Hospitals Choose Us

We supply and service bilevel and ventilator-class devices for hospital and home-care use across Chennai, with dedicated technical support for clinical teams.

Why Patients Prefer Us

Home delivery, hands-on setup training, and ongoing technical support are included with every Prisma 25ST purchase or rental — not sold as a separate add-on.

Prisma 25ST vs Prisma 25S

Löwenstein also makes the Prisma 25S — a closely related BiPAP that shares the Prisma 25ST's chassis, pressure range and near-silent operation, but is built for a different clinical need. The table below highlights the real difference that should guide which one a physician prescribes.

Feature	Prisma 25S	Prisma 25ST
Modes	CPAP, Auto BiPAP, BiPAP (S)	CPAP, APAP, S, T, S/T, autoS, autoS/T
Automatic backup breath	No	Yes — autoBackup Frequency (PRIO S+)
Apnea differentiation (FOT)	Yes	Yes, plus autoTriLevel comfort adjustment
Pressure range	4–25 hPa	IPAP 4–25 hPa / EPAP 4–20 hPa
Sound level	≈26.5 dB(A)	≈26.5 dB(A)
Weight	≈1.4 kg	≈1.4 kg
Typically prescribed for	Patients who need bilevel pressure support but not an automatic backup breath	Patients whose breathing can pause and who need a guaranteed backup breath — complex/central apnea, COPD hypoventilation, neuromuscular disease

In short: the Prisma 25S and Prisma 25ST use the same platform, but only the 25ST adds the Timed backup-breath mode — the safety feature this page is about. Your pulmonologist or sleep physician decides which model fits your diagnosis; Srivari Healthcare can supply either as an authorised Löwenstein Medical dealer.

💬 WhatsApp us to confirm which model your prescription needs, or 📞 call +91 99410 64349 to speak with our team.

Prisma 25ST in Chennai & Tamil Nadu

Srivari Healthcare supplies, installs and services the Prisma 25ST across Chennai and Tamil Nadu, including home delivery, patient/caregiver training on device use, and ongoing technical support. For hospitals and sleep labs, we also support bulk supply and servicing arrangements.