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The prisma25ST by Löwenstein Medical is an advanced BiLevel ST sleep and ventilation therapy device designed for patients who require controlled respiratory support. It is ideal for individuals with obstructive, mixed, or central sleep apnea, as well as patients with hypoventilation syndromes or neuromuscular and respiratory disorders. By combining spontaneous breathing support with a timed backup rate, prisma25ST ensures reliable ventilation even when spontaneous breathing is insufficient.
Equipped with a large, intuitive color touchscreen and user-friendly smart navigation, prisma25ST enables quick setup and effortless operation for both clinicians and patients. The device offers advanced pressure and ventilation control features such as adjustable backup rate, Ti control, softPAP pressure relief, and softSTART ramp, ensuring comfortable, synchronized, and effective therapy throughout the night.
Comprehensive monitoring and connectivity options — including SD card, LAN, and telemedicine compatibility via prisma CLOUD and prisma APP — allow seamless therapy tracking, data sharing, and remote clinical review. When combined with the prismaAQUA humidifier and optional heated breathing circuit, prisma25ST delivers warm, humidified airflow for enhanced patient comfort and long-term compliance.
Key Features
- BiLevel ST therapy mode: Spontaneous/Timed ventilation with adjustable backup rate for reliable respiratory support.
- Wide pressure range: Adaptive pressure delivery from 4 to 25 cmH₂O.
- Advanced comfort functions: softPAP for reduced exhalation effort and softSTART ramp for gentle therapy initiation.
- Breath synchronization control: Precise trigger and cycle sensitivity with Ti (inspiratory time) settings.
- Large color touchscreen: Clear display for easy monitoring and intuitive operation.
- Modern connectivity: SD card, LAN, prisma APP and CLOUD for therapy data management.
- Humidifier compatibility: Supports prismaAQUA humidifier and heated circuit for optimal humidification.
Ideal For
- Patients with central or mixed sleep apnea
- Users requiring backup respiratory rate support
- Patients with neuromuscular or respiratory insufficiency
- Homecare and clinical ventilation environments
Ganesan – chennai –
“I am using the Prisma 25ST for my sleep problem. My breathing is better now and I sleep peacefully. The machine is quiet and easy to use. I feel more active in the morning.”
Ganesan – chennai
Dr. Vivek Sharma – Sleep Specialist –
“In my clinical practice, the Prisma 25ST has shown good patient comfort and consistent therapeutic outcomes.”
Dr. Vivek Sharma – Sleep Specialist
Abdul Rahman, Bangalore –
“My oxygen levels improved and I feel more energetic during the day. The pressure changes are smooth and don’t disturb my sleep.”
Abdul Rahman, Bangalore
Dr. Ramesh Patel –
I recommend Prisma 25ST for COPD, OSA, and moderate NIV patients. Stable pressure and easy operation help with adherence. Most of my patients show improved oxygen saturation and quality sleep.
Dr. Ramesh Patel, Respiratory Specialist – T. Nagar, Chennai
Dr. Rahul Menon, Respiratory Physician –
“The Prisma 25ST is a dependable option for chronic respiratory insufficiency. Its monitoring features and pressure stability make long-term therapy management easier.”
Dr. Rahul Menon, Respiratory Physician
Dr. R. Narasimhan – Apollo Hospitals, Chennai –
“The Prisma 25ST is effective for patients with moderate to severe sleep apnea and COPD. It provides stable BiLevel-ST support with a reliable backup rate. Patients show improved oxygen levels and better sleep quality. The device is easy to manage in both hospital and home settings. I often recommend it when CPAP therapy is not sufficient.”
Dr. R. Narasimhan – Apollo Hospitals, Chennai
Naveen Raj, –
I started using Prisma 25ST due to moderate breathing difficulty at night. The pressure transitions feel smooth and comfortable. My sleep has become deeper and I wake up refreshed in the mornings. Great support for home therapy.
Naveen Raj, Velachery, Chennai
Joseph Mathew – Kochi –
“My father uses this machine for COPD support at night. His breathing has improved significantly.”
Joseph Mathew – Kochi
Murali Krishna –
The setup was simple and the therapy feels stable throughout the night. I noticed fewer breathing pauses and improved sleep quality.
Murali Krishna – Vijayawada
Dr. Lakshmi Iyer –
Prisma 25ST is suitable for moderate respiratory insufficiency cases. It provides consistent pressure and good patient comfort. Compliance levels among my patients are encouraging.
Dr. Lakshmi Iyer, Pulmonologist – Chennai
Naveen Raj –
Prisma 25ST helped reduce my breathlessness during sleep. The machine adapts well to my breathing pattern. I wake up fresher and less exhausted.
Naveen Raj – Salem
Dr. Rahul Menon – Respiratory Consultant –
“I appreciate the quiet operation and detailed therapy monitoring of this machine. It allows accurate evaluation of patient progress.”
Dr. Rahul Menon – Respiratory Consultant
Meena Latha –
I was unsure at first, but after using Prisma 25ST for a month, I noticed big improvements. No frequent waking up, and my oxygen levels are more stable. Comfortable and quiet machine.
Meena Latha, Madipakkam, Chennai
Dr. Vivek Nangia – Max Super Speciality Hospital, Delhi –
“This machine offers consistent pressure support and good patient synchronization. It helps manage respiratory insufficiency effectively during sleep. The airflow is smooth, and patients adapt comfortably over time. It is a dependable option for long-term therapy. Overall, a practical and efficient BiPAP device.”
Dr. Vivek Nangia – Max Super Speciality Hospital, Delhi
Dr. Arvind Kumar – Pulmonologist –
“I frequently recommend the Prisma 25ST for chronic respiratory insufficiency. The intelligent pressure profiles and quiet operation improve patient comfort and compliance.”
Dr. Arvind Kumar – Pulmonologist
Dr. R. Narasimhan – Pulmonologist –
“The Prisma 25ST provides stable BiLevel-ST ventilation for patients with complex sleep apnea and COPD. Its automatic backup rate ensures continuous breathing support during sleep.”
Dr. R. Narasimhan – Pulmonologist
Dr. Arvind Nair – Respiratory Physician –
“The Prisma 25ST provides a wide pressure range and multiple ventilation modes. It is particularly useful for patients who require reliable BiPAP ST therapy and long-term respiratory support.”
Dr. Arvind Nair – Respiratory Physician
Priya Srinivasan –
My nighttime breathlessness reduced significantly after using this BiPAP. The transitions between pressure settings feel smooth and therapy feels very effective. I am satisfied with this machine.
Priya Srinivasan, Royapuram, Chennai
Abdul Rahman – Hyderabad –
This BiPAP machine is very quiet and comfortable. The pressure adjusts smoothly, so breathing feels natural during sleep.
Abdul Rahman – Hyderabad
Dr. Meena Subramanian – Sleep Medicine Specialist –
“This device offers excellent patient-ventilator synchrony. Features like FOT-based apnea detection and flexible pressure settings make therapy more accurate and effective.”
Dr. Meena Subramanian – Sleep Medicine Specialist
M. Ganesan – chennai –
“My doctor recommended this BiPAP for my night breathing problems. After using the Prisma 25ST, my sleep improved and I wake up feeling less tired.”
M. Ganesan – chennai
Dr. Arun Gupta –
Prisma 25ST provides consistent IPAP/EPAP support with excellent synchrony. It’s suitable for long-term home NIV, especially for moderate respiratory weakness. Home monitoring shows improved patient comfort and positive clinical outcomes.
Dr. Arun Gupta, Chest Physician – Chennai
Dr. M. Srinivasan, Pulmonologist –
“I prescribe the Prisma 25ST for patients who need bilevel therapy with backup rate support. The device provides stable pressure delivery and helps reduce nocturnal CO₂ retention in COPD cases.”
Dr. M. Srinivasan, Pulmonologist
Thomas Reilly –
I was anxious about pressure comfort, but this machine handled it well. Prisma 25ST adjusted to my breathing and provided steady support all night. I manage my condition much better now.
Thomas Reilly, COPD Patient – London, UK
Jagan _ chennai –
“This machine works well for patients who need higher pressure support. It adjusts breathing and helps maintain oxygen levels during sleep. Easy to set and reliable for home use. Overall, a good advanced therapy device.”
Jagan _ chennai
Dr. Nisha Reddy, Sleep Medicine Specialist –
“This machine offers good patient-ventilator synchrony and reliable ST mode. Many of my patients show improved oxygen saturation and reduced sleep disturbances after starting therapy.”
Dr. Nisha Reddy, Sleep Medicine Specialist
Rajesh Kumar, Chennai –
“I was advised this BiPAP for night breathing problems. After using Prisma 25ST, I feel less breathless in the morning and sleep longer without waking.”
Rajesh Kumar, Chennai
Dr. Vivek Nangia – Respiratory Medicine Specialist –
“This device offers excellent flexibility with multiple ventilation modes and precise pressure control. It is highly effective for patients who cannot tolerate CPAP therapy.”
Dr. Vivek Nangia – Respiratory Medicine Specialist
Jayasree N –
We chose this model for my husband after consulting our doctor. It’s compact, quiet, and easy to clean. His oxygen levels have improved during sleep.
Jayasree N – Chennai
Dr. Dinesh Kumar – Medanta Hospital, Gurugram –
“The Prisma 25ST provides flexible therapy with multiple ventilation modes. It is suitable for patients requiring additional breathing support beyond CPAP. The backup rate ensures continuous ventilation even during apnea events. I have observed better compliance in patients using this device. It performs well in home care.”
. Dr. Dinesh Kumar – Medanta Hospital, Gurugram